PTGEs/Prostaglandin E Synthase Polyclonal Antibody, AbBy Fluor-488 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-1880R-BF488 |
| Product Name | PTGEs/Prostaglandin E Synthase Polyclonal Antibody, AbBy Fluor-488 Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, GuineaPig |
| Specifications | |
| Conjugation | AbBy Fluor-488 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human PTGEs |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 9536 |
| Swiss Prot | O14684 |
| Subcellular location | Cell membrane |
| Synonyms | PGES; MPGES; PIG12; PP102; PP1294; MGST-IV; MGST1L1; TP53I12; mPGES-1; MGST1-L1; Prostaglandin E synthase; Microsomal glutathione S-transferase 1-like 1; Microsomal prostaglandin E synthase 1; p53-induced gene 12 protein; PTGES; MPGES1 |
| Background | Prostaglandin E synthase catalyses conversion of COX derived PGH2 to PGE2. It is a member of the MAPEG family. It may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain during inflammatory responses.The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is PTGEs/Prostaglandin E Synthase Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-1880R-BF488) validated for, and at what dilution?
bs-1880R-BF488 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does PTGEs/Prostaglandin E Synthase Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-1880R-BF488) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat, GuineaPig.
How should bs-1880R-BF488 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise PTGEs/Prostaglandin E Synthase Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-1880R-BF488)?
KLH conjugated synthetic peptide derived from human PTGEs
What are the excitation and emission wavelengths of the AbBy Fluor-488 conjugate (bs-1880R-BF488)?
AbBy Fluor-488 on bs-1880R-BF488: excitation / emission 499nm/519nm.