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TGM3 Polyclonal Antibody, HRP Conjugated

Applications

  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Dog
  • Cow
  • Horse
  • Rabbit
Overview
Catalog # bs-1911R-HRP
Product Name TGM3 Polyclonal Antibody, HRP Conjugated
Applications ELISA, IHC-P, IHC-F
Reactivity Mouse, Rat
Predicted Reactivity Human, Dog, Cow, Horse, Rabbit
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human TGM3
Immunogen Range 601-693/693
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 7053
Swiss Prot Q08188
Subcellular location Cytoplasm
Synonyms TGE; Protein-glutamine gamma-glutamyltransferase E; Transglutaminase E; TG(E); TGase E; Transglutaminase-3; TGase-3; TGM3
Background Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500