NTAN1 Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-19495R-100uL |
| Product Name | NTAN1 Polyclonal Antibody |
| Applications |
IHC-P
IHC-F
IF
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human NTAN1 |
| Immunogen Range | 111-210/310 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 123803 |
| Swiss Prot | Q96AB6 |
| Synonyms | N terminal Asn amidase; N terminal asparagine amidase; N terminal asparagine amidohydrolase; NTN-amidase; PNAA; PNAD; Protein N-terminal Asn amidase; Protein N-terminal asparagine amidase; Protein N-terminal asparagine amidohydrolase; Protein NH2-terminal asparagine amidohydrolase; Protein NH2-terminal asparagine deamidase; Protein NTN-amidase. |
| Background | The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012] |
| Application Dilution | |
| IHC-P | 1:200-400 |
| IHC-F | |
| IF | |
Frequently asked questions
Which applications is NTAN1 Polyclonal Antibody (bs-19495R) validated for, and at what dilution?
bs-19495R is validated for IHC-P (1:200-400). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does NTAN1 Polyclonal Antibody (bs-19495R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-19495R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise NTAN1 Polyclonal Antibody (bs-19495R)?
KLH conjugated synthetic peptide derived from human NTAN1 Immunogen range: 111-210/310.