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RAB11-FIP2 Polyclonal Antibody

Applications

  • WB
  • ELISA

Reactivity

  • Human
  • Mouse

Predicted Reactivity

  • Rat
  • Dog
  • Cow
  • Pig
  • Horse
  • Chicken
  • Cat
  • Rabbit
  • Guinea Pig
Overview
Catalog # bs-19705R
Product Name RAB11-FIP2 Polyclonal Antibody
Applications WB, ELISA
Reactivity Human, Mouse
Predicted Reactivity Rat, Dog, Cow, Pig, Horse, Chicken, Cat, Rabbit, Guinea Pig
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human RAB11-FIP2
Immunogen Range 331-430/512
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 22841
Swiss Prot Q7L804
Subcellular location Cell membrane
Synonyms RAB11FIP2;KIAA0941; NRip11; RAB11 family interacting protein 2 (class I); Rab11 family-interacting protein 2; RAB11 FIP2 long isoform; Rab11-FIP2; RFIP2; RFIP2_HUMAN.
Background A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000