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phospho-Parkin (Ser131) Polyclonal Antibody, Cy7 Conjugated

Applications

  • IF(ICC)
  • IF

Reactivity

  • Human

Predicted Reactivity

  • Cow
Overview
Catalog # bs-19881R-Cy7
Product Name phospho-Parkin (Ser131) Polyclonal Antibody, Cy7 Conjugated
Applications IF(ICC), IF
Reactivity Human
Predicted Reactivity Cow
Specifications
Conjugation Cy7
Host Rabbit
Source KLH conjugated synthesised phosphopeptide derived from human Parkin around the phosphorylation site of Ser131.
Modification Site Ser131
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 5071
Swiss Prot O60260
Synonyms Parkin (phospho S131); p-Parkin (phospho S131); AR JP; E3 ubiquitin ligase; E3 ubiquitin protein ligase parkin; E3 ubiquitin-protein ligase parkin; FRA6E; LPRS 2; LPRS2; PARK 2; PARK2; Parkin 2; Parkinson disease (autosomal recessive juvenile) 2; Parkinson disease (autosomal recessive, juvenile) 2, parkin; Parkinson disease protein 2; Parkinson juvenile disease protein 2; Parkinson protein 2 E3 ubiquitin protein ligase; Parkinson protein 2, E3 ubiquitin protein ligase (parkin); PDJ; PRKN 2; PRKN; PRKN2; PRKN2_HUMAN; Ubiquitin E3 ligase PRKN.
Background The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
Application Dilution
IF(ICC)
IF