GRINA Polyclonal Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-20059r |
| Product Name | GRINA Polyclonal Antibody |
| Applications |
IHC-P
IHC-F
IF(ICC)
IF
|
| Reactivity | Mouse, Rat |
| Predicted Reactivity | Human, Cow, Sheep, Rabbit |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human GRINA |
| Immunogen Range | 1-100/371 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 2907 |
| Swiss Prot | Q7Z429 |
| Synonyms | Glutamate [NMDA] receptor associated protein 1; Glutamate receptor, ionotropic, N methyl D aspartate associated protein 1 (glutamate binding); Glutamate receptor, NMDA subtype, glutamate binding subunit; HNRGW; LFG1; MGC99687; NMDA receptor glutamate binding subunit; NMDARA1; Putative MAPK activating protein PM02; TMBIM3; Transmembrane BAX inhibitor motif containing 3; LFG1_HUMAN. |
| Background | Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. As one of the four major proteins of the NMDA receptor ion channel, GRINA (Glutamate [NMDA] receptor-associated protein 1), also designated NMDA receptor glutamate-binding subunit or putative MAPK-activating protein PM02, is a 371 amino acid multi-pass transmembrane protein. Due to the chromosomal location of the gene encoding GRINA, studies have linked possible GRINA involvement with a form of idiopathic generalized epilepsy. |
| Application Dilution | |
| IHC-P | |
| IHC-F | |
| IF(ICC) | |
| IF | |
Frequently asked questions
Which applications is GRINA Polyclonal Antibody (bs-20059R) validated for, and at what dilution?
bs-20059R is validated for IHC-P, IHC-F, IF(ICC), IF.
Which species does GRINA Polyclonal Antibody (bs-20059R) react with?
Tested reactivity: Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human, Cow, Sheep, Rabbit.
How should bs-20059R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise GRINA Polyclonal Antibody (bs-20059R)?
KLH conjugated synthetic peptide derived from human GRINA Immunogen range: 1-100/371.