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HSD11B2 Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • IHC-F

Reactivity

  • Human
  • Mouse
  • Rat

Predicted Reactivity

  • Dog
  • Horse
Overview
Catalog # bs-20186R-Biotin
Product Name HSD11B2 Polyclonal Antibody, Biotin Conjugated
Applications
WB IHC-F
Reactivity Human, Mouse, Rat
Predicted Reactivity Dog, Horse
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human HSD11B2
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C for 12 months.
Target
Gene ID 3291
Swiss Prot P80365
Subcellular location Cytoplasm
Synonyms AME; AME1; HSD2; HSD11K; SDR9C3; Corticosteroid 11-beta-dehydrogenase isozyme 2; 11-beta-hydroxysteroid dehydrogenase type 2; 11-DH2; 11-beta-HSD2; 11-beta-hydroxysteroid dehydrogenase type II; 11-HSD type II; 11-beta-HSD type II; NAD-dependent 11-beta-hydroxysteroid dehydrogenase; 11-beta-HSD; Short chain dehydrogenase/reductase family 9C member 3; HSD11B2
Background Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Application Dilution
WB 1:300-5000
IHC-F 1:100-500

Frequently asked questions

Which applications is HSD11B2 Polyclonal Antibody, Biotin Conjugated (bs-20186R-Biotin) validated for, and at what dilution?

bs-20186R-Biotin is validated for WB (1:300-5000); IHC-F (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does HSD11B2 Polyclonal Antibody, Biotin Conjugated (bs-20186R-Biotin) react with?

Tested reactivity: Human, Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Dog, Horse.

How should bs-20186R-Biotin be stored?

Store at -20C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise HSD11B2 Polyclonal Antibody, Biotin Conjugated (bs-20186R-Biotin)?

KLH conjugated synthetic peptide derived from human HSD11B2