Integrin alpha 3 Polyclonal Antibody

Applications

  • WB
  • ELISA
  • FCM
  • IHC-P

Reactivity

  • Mouse
  • Pig

Predicted Reactivity

  • Human
  • Rat
Overview
Catalog # bs-2093R
Product Name Integrin alpha 3 Polyclonal Antibody
Applications WB, ELISA, FCM, IHC-P
Reactivity Mouse, Pig
Predicted Reactivity Human, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Integrin alpha 3
Immunogen Range 976-1025/1051
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 3675
Swiss Prot P26006
Subcellular location Cell membrane
Synonyms VL3A; CD49C; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3; Integrin alpha-3; CD49 antigen-like family member C; FRP-2; Galactoprotein B3; VLA-3 subunit alpha; ITGA3
Background Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Application Dilution
WB 1:500-2000
ELISA 1:5000-10000
FCM 1:100
IHC-P 1:100-500