Ki-67 (Proliferation Marker) Antibody

Applications

  • ELISA
  • FCM
  • IHC-P
  • IHC-F

Reactivity

  • Human
  • Mouse
  • Rabbit

Predicted Reactivity

  • Rat
Overview
Catalog # bs-2130R
Product Name Ki-67 (Proliferation Marker) Antibody
Applications ELISA, FCM, IHC-P, IHC-F
Reactivity Human, Mouse, Rabbit
Predicted Reactivity Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Ki67
Immunogen Range 1201-1300/3256
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 4288
Swiss Prot P46013
Subcellular location Nucleus
Synonyms KIA; MIB-; MIB-1; PPP1R15; Antigen KI-67; MKI67
Background Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
Application Dilution
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500