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NR3C2/Mineralocorticoid receptor Polyclonal Antibody, PE-Cy5.5 Conjugated

Applications

  • WB

Reactivity

  • Rat

Predicted Reactivity

  • Human
  • Mouse
Overview
Catalog # bs-21357R-PE-Cy5.5-100uL
Product Name NR3C2/Mineralocorticoid receptor Polyclonal Antibody, PE-Cy5.5 Conjugated
Applications
WB
Reactivity Rat
Predicted Reactivity Human, Mouse
Specifications
Conjugation PE-Cy5.5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human NR3C2/Mineralocorticoid receptor
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 4306
Swiss Prot P08235
Subcellular location Cytoplasm, Nucleus, Cell membrane
Synonyms Aldosterone receptor; MCR; MGC133092; MLR; MR; NR3 C2; NR3C2; NR3C2 protein; Nuclear receptor subfamily 3 group C member 2; MCR_HUMAN.
Background Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Application Dilution
WB 1:300-5000

Frequently asked questions

Which applications is NR3C2/Mineralocorticoid receptor Polyclonal Antibody, PE-Cy5.5 Conjugated (BS-21357R-PE-CY5-5) validated for, and at what dilution?

BS-21357R-PE-CY5-5 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does NR3C2/Mineralocorticoid receptor Polyclonal Antibody, PE-Cy5.5 Conjugated (BS-21357R-PE-CY5-5) react with?

Tested reactivity: Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human, Mouse.

How should BS-21357R-PE-CY5-5 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise NR3C2/Mineralocorticoid receptor Polyclonal Antibody, PE-Cy5.5 Conjugated (BS-21357R-PE-CY5-5)?

KLH conjugated synthetic peptide derived from human NR3C2/Mineralocorticoid receptor

What are the excitation and emission wavelengths of the PE-Cy5.5 conjugate (BS-21357R-PE-CY5-5)?

PE-Cy5.5 on BS-21357R-PE-CY5-5: excitation / emission 488nm/694nm.