FOXD2 Polyclonal Antibody, Cy3 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-21592R-Cy3-100uL |
| Product Name | FOXD2 Polyclonal Antibody, Cy3 Conjugated |
| Applications |
WB
|
| Reactivity | Human, Mouse |
| Predicted Reactivity | Rat, Cow, Pig, Rabbit |
| Specifications | |
| Conjugation | Cy3 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human FOXD2 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 2306 |
| Swiss Prot | O60548 |
| Synonyms | Drosphilia Forkhead Homolog Like 17; FKHL 17; Forkhead box protein D2; Forkhead Related Activator 9; Forkhead-related protein FKHL17; Forkhead-related transcription factor 9; FOXD2; FOXD2_HUMAN; FREAC 9; FREAC-9. |
| Background | The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. FOXD1 (also designated Brain Factor 2 or BF-2) is involved in regulating inflammation as well as kidney and retinal development. FOXD1 regulates the activity of NF-AT and NFkB. Deficiency of FOXD1 results in multiorgan, systemic inflammation, exaggerated Th cell-derived cytokine production, and T cell proliferation in autogolgous MLRs. In kidneys, FOXD1 controls the production of signals required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system. Deletion of FOXD1 results in renal abnormalities. FOXD2 acts as a modulator of T cell activation. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is FOXD2 Polyclonal Antibody, Cy3 Conjugated (bs-21592R-Cy3) validated for, and at what dilution?
bs-21592R-Cy3 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does FOXD2 Polyclonal Antibody, Cy3 Conjugated (bs-21592R-Cy3) react with?
Tested reactivity: Human, Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Rat, Cow, Pig, Rabbit.
How should bs-21592R-Cy3 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise FOXD2 Polyclonal Antibody, Cy3 Conjugated (bs-21592R-Cy3)?
KLH conjugated synthetic peptide derived from human FOXD2
What are the excitation and emission wavelengths of the Cy3 conjugate (bs-21592R-Cy3)?
Cy3 on bs-21592R-Cy3: excitation / emission 512,550nm/570,615nm.