TNFR1 Polyclonal Antibody, AbBy Fluor-750 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-22306R-BF750 |
| Product Name | TNFR1 Polyclonal Antibody, AbBy Fluor-750 Conjugated |
| Applications |
WB
IF
|
| Reactivity | Human |
| Specifications | |
| Conjugation | AbBy Fluor-750 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human TNFR1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/ml |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 7132 |
| Swiss Prot | P19438 |
| Subcellular location | Secreted, Cell membrane |
| Synonyms | TNFRSF1a; CD120a; CD120a antigen; MGC19588; p55; p55 R; p55R; p60; TBP1; TBPI; TNF R; TNF R I; TNF R1; TNF R55; TNF-R1; Soluble TNF Receptor I; Soluble TNF p55 Receptor; TNF-RI; TNFR 1; TNFR I; TNFR-I; TNFR55; TNFR60; TNFRI; TNFRSF1a; TNR1A_HUMAN; Tumor necrosis factor alpha receptor; Tumor necrosis factor binding protein 1; Tumor necrosis factor receptor 1; Tumor necrosis factor receptor type 1; Tumor necrosis factor receptor type I; Tumor necrosis factor-binding protein 1. |
| Background | Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. |
| Application Dilution | |
| WB | =1:500-2000 |
| IF | |
Frequently asked questions
Which applications is TNFR1 Polyclonal Antibody, AbBy Fluor-750 Conjugated (bs-22306R-BF750) validated for, and at what dilution?
bs-22306R-BF750 is validated for WB (WB=1:500-2000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does TNFR1 Polyclonal Antibody, AbBy Fluor-750 Conjugated (bs-22306R-BF750) react with?
Tested reactivity: Human.
How should bs-22306R-BF750 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise TNFR1 Polyclonal Antibody, AbBy Fluor-750 Conjugated (bs-22306R-BF750)?
KLH conjugated synthetic peptide derived from human TNFR1
What are the excitation and emission wavelengths of the AbBy Fluor-750 conjugate (bs-22306R-BF750)?
AbBy Fluor-750 on bs-22306R-BF750: excitation / emission 749nm/775nm.