IL-4R Polyclonal Antibody, FITC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-22901R-FITC-100uL |
| Product Name | IL-4R Polyclonal Antibody, FITC Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | FITC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human IL-4R |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 3566 |
| Swiss Prot | P24394 |
| Subcellular location | Secreted, Cell membrane |
| Synonyms | CD124; IL 4R alpha; IL-4 receptor subunit alpha; IL-4-binding protein; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; IL4-BP; Il4r; IL4R nirs variant 1; IL4RA; IL4RA_HUMAN; Interleukin 4 receptor alpha chain; Interleukin 4 receptor; sIL4Ralpha/prot; Soluble IL-4 receptor subunit alpha; Soluble IL-4R-alpha; Soluble interleukin-4 receptor subunit alpha. |
| Background | Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammmation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is IL-4R Polyclonal Antibody, FITC Conjugated (bs-22901R-FITC) validated for, and at what dilution?
bs-22901R-FITC is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does IL-4R Polyclonal Antibody, FITC Conjugated (bs-22901R-FITC) react with?
Tested reactivity: Human.
How should bs-22901R-FITC be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise IL-4R Polyclonal Antibody, FITC Conjugated (bs-22901R-FITC)?
KLH conjugated synthetic peptide derived from human IL-4R
What are the excitation and emission wavelengths of the FITC conjugate (bs-22901R-FITC)?
FITC on bs-22901R-FITC: excitation / emission 494nm/518nm.