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Bak Polyclonal Antibody, AbBy Fluor-750 Conjugated

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bs-22928R-BF750-100uL
Product Name Bak Polyclonal Antibody, AbBy Fluor-750 Conjugated
Applications
WB
Reactivity Human
Specifications
Conjugation AbBy Fluor-750
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Bak
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 578
Swiss Prot O08734
Subcellular location Cytoplasm, Cell membrane
Synonyms Apoptosis Regulator Bak; BAK 1; BAK; BAK like; Bak NT; BAK1; Bcl 2 homologous antagonist/killer; Bcl 2 like 7 protein; Bcl2 homologous antagonist killer; Bcl2 like 7 Protein; BCL2-antagonist/killer 1; BCL2L7; CDN 1; CDN1; Cell death inhibitor 1; MGC117255; MGC3887; NBak; Pro apoptotic protein BAK; BAK_HUMAN; BAK_MOUSE
Background The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
Application Dilution
WB 1:300-5000

Frequently asked questions

Which applications is Bak Polyclonal Antibody, AbBy Fluor-750 Conjugated (bs-22928R-BF750) validated for, and at what dilution?

bs-22928R-BF750 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does Bak Polyclonal Antibody, AbBy Fluor-750 Conjugated (bs-22928R-BF750) react with?

Tested reactivity: Human.

How should bs-22928R-BF750 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise Bak Polyclonal Antibody, AbBy Fluor-750 Conjugated (bs-22928R-BF750)?

KLH conjugated synthetic peptide derived from human Bak

What are the excitation and emission wavelengths of the AbBy Fluor-750 conjugate (bs-22928R-BF750)?

AbBy Fluor-750 on bs-22928R-BF750: excitation / emission 749nm/775nm.