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ABCA1 Polyclonal Antibody, Biotin Conjugated

Applications

  • IHC-P
  • IHC-F

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
Overview
Catalog # bs-23419r-biotin-100l
Product Name ABCA1 Polyclonal Antibody, Biotin Conjugated
Applications IHC-P, IHC-F
Reactivity Human
Predicted Reactivity Mouse, Rat
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human ABCA1
Immunogen Range 501-600/2261
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Affinity purified by Protein A
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 19
Swiss Prot O95477
Subcellular location Extracellular
Synonyms ABC-1; ABC1; CERP; HDLCQTL13; TGD; ABCA1_HUMAN; ABCA1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1 (ABC-1 | ATP-binding cassette 1); cassette subfamily A member 1; ATP-binding cassette, sub-family A (ABC1), member 1; Tangier disease
Background ABCA1 is a membrane-associated ATP-binding cassette transporter involved in cellular lipid homeostasis. It promotes the efflux of cholesterol and phospholipids to apolipoproteins, supporting the formation of nascent high-density lipoproteins (HDLs). ABCA1 preferentially transports phosphatidylcholine and plays an important role in cholesterol removal pathways. Mutations in ABCA1 are associated with Tangier disease and familial HDL deficiency, making it a relevant marker for lipid metabolism, cholesterol transport, cardiovascular research, and related disease studies.
Application Dilution
IHC-P 1:100-500
IHC-F 1:100-500