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ABCA1 Polyclonal Antibody, RBITC Conjugated

Applications

  • IF

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
Overview
Catalog # bs-23419r-rbitc-100l
Product Name ABCA1 Polyclonal Antibody, RBITC Conjugated
Applications IF
Reactivity Human
Predicted Reactivity Mouse, Rat
Specifications
Conjugation RBITC
Host Rabbit
Source KLH conjugated synthetic peptide derived from human ABCA1
Immunogen Range 501-600/2261
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Affinity purified by Protein A
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 19
Swiss Prot O95477
Subcellular location Extracellular
Synonyms ABC-1; ABC1; CERP; HDLCQTL13; TGD; ABCA1_HUMAN; ABCA1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1 (ABC-1 | ATP-binding cassette 1); cassette subfamily A member 1; ATP-binding cassette, sub-family A (ABC1), member 1; Tangier disease
Background ABCA1 is a membrane-associated ATP-binding cassette transporter involved in cellular lipid homeostasis. It promotes the efflux of cholesterol and phospholipids to apolipoproteins, supporting the formation of nascent high-density lipoproteins (HDLs). ABCA1 preferentially transports phosphatidylcholine and plays an important role in cholesterol removal pathways. Mutations in ABCA1 are associated with Tangier disease and familial HDL deficiency, making it a relevant marker for lipid metabolism, cholesterol transport, cardiovascular research, and related disease studies.
Application Dilution
IF 1:100-500