TGF beta Receptor I Polyclonal Antibody

Lane 1: Human K562 cell lysates; Lane 2: Human SH-SY5Y cell lysates probed with TGF beta Receptor I Polyclonal Antibody, Unconjugated (bs-23445R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.

Lane 1: Human Hela cell lysates; Lane 2: Human HepG2 cell lysates; Lane 3: Human Raji cell lysates; Lane 4: Human U87MG cell lysates ; Lane 5: Human K562 cell lysates probed with TGF beta Receptor I Polyclonal Antibody, Unconjugated (bs-23445R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.

Applications

WB
ELISA
IHC-P
IHC-F
IF

Reactivity

Human

Predicted Reactivity

Mouse
Rat
Dog
Cow
Sheep
Pig
Horse
Chicken
Rabbit

Overview
Catalog #	bs-23445R
Product Name	TGF beta Receptor I Polyclonal Antibody
Applications	WB, ELISA, IHC-P, IHC-F, IF
Reactivity	Human
Predicted Reactivity	Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human TGF beta Receptor I
Clonality	Polyclonal
Clone #	#REF!
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	7046
Swiss Prot	P36897
Subcellular location	Cell membrane
Synonyms	TGFBR1; TGF Beta R1; TGF beta Receptor I; AAT 5; AAT5; Activin A receptor type II like kinase 53kDa; Activin receptor like kinase 5; ACVRLK 4; ACVRLK4; ALK 5; ALK5; Serine/threonine protein kinase receptor R4; SKR 4; SKR4; TbetaR I; TGF beta receptor type 1; TGF beta receptor type I; TGF beta type I receptor; TGFBR 1; TGFBR1 protein; TGFR 1; TGFR1; Transforming growth factor beta receptor I;TGF-??R???????; TGF??R???????; TGF-??R ???????; TGF-?? R???????.
Background	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.
Application Dilution
WB	1:300-5000
ELISA	1:500-1000
IHC-P	1:200-400
IHC-F	1:100-500
IF