Free Shipping On Orders Over $1,000!

PKA C alpha+beta Polyclonal Antibody, HRP Conjugated

Applications

  • WB
  • ELISA
  • IHC-P

Reactivity

  • Human
  • Mouse
  • Rat

Predicted Reactivity

  • Dog
  • Cow
  • Pig
  • Chicken
Overview
Catalog # bs-2371R-HRP
Product Name PKA C alpha+beta Polyclonal Antibody, HRP Conjugated
Applications WB, ELISA, IHC-P
Reactivity Human, Mouse, Rat
Predicted Reactivity Dog, Cow, Pig, Chicken
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human PKA beta
Immunogen Range 251-351/351
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 81491
Subcellular location Cytoplasm, Nucleus, Cell membrane
Synonyms PKA C beta; PKACB; PRKACB; Protein kinase cAMP dependent catalytic beta.
Background cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. PKA beta (catalytic subunit) is a member of the Ser/Thr protein kinase family and is a catalytic subunit of AMPK.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400