NCR3 Polyclonal Antibody, Cy3 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-2418R-Cy3 |
| Product Name | NCR3 Polyclonal Antibody, Cy3 Conjugated |
| Applications |
FCM
|
| Reactivity | Human |
| Predicted Reactivity | Rat, Dog, Horse, Rabbit |
| Specifications | |
| Conjugation | Cy3 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human NCR3 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 259197 |
| Swiss Prot | O14931 |
| Subcellular location | Cell membrane |
| Synonyms | 1C7; MALS; CD337; LY117; NKp30; Natural cytotoxicity triggering receptor 3; Activating natural killer receptor p30; Natural killer cell p30-related protein; NK-p30; NCR3 |
| Background | Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation. |
| Application Dilution | |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is NCR3 Polyclonal Antibody, Cy3 Conjugated (bs-2418R-Cy3) validated for, and at what dilution?
bs-2418R-Cy3 is validated for FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does NCR3 Polyclonal Antibody, Cy3 Conjugated (bs-2418R-Cy3) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Rat, Dog, Horse, Rabbit.
How should bs-2418R-Cy3 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise NCR3 Polyclonal Antibody, Cy3 Conjugated (bs-2418R-Cy3)?
KLH conjugated synthetic peptide derived from human NCR3
What are the excitation and emission wavelengths of the Cy3 conjugate (bs-2418R-Cy3)?
Cy3 on bs-2418R-Cy3: excitation / emission 512,550nm/570,615nm.