CYP21 Polyclonal Antibody, Biotin Conjugated

Applications

  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Rat

Predicted Reactivity

  • Human
  • Mouse
  • Dog
  • Cow
  • Pig
  • Horse
Overview
Catalog # bs-2443R-Biotin
Product Name CYP21 Polyclonal Antibody, Biotin Conjugated
Applications ELISA, IHC-P, IHC-F
Reactivity Rat
Predicted Reactivity Human, Mouse, Dog, Cow, Pig, Horse
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CYP21
Immunogen Range 101-200/494
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 1589
Subcellular location Cytoplasm, Cell membrane
Synonyms Cytochrome P450 21; cytochrome P450, family 21, subfamily A, polypeptide 2; 21-OH; 21OHA; 21OHB; CA21H; CAH1; CHOLESTEROL 21-HYDROXYLASE; CPS1; CYP21; Cyp21-ps1; Cyp21a1; CYP21A2; Cyp21a2-ps; CYP21B; CYP21OH-A; MGC150536; MGC150537; MGC156449; Oh21-1; Oh21-2; P450C21; P450c21B; CYP21A2; CP21A_HUMAN.
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500