Polycystin 2 Polyclonal Antibody, AbBy Fluor-750 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-24450R-BF750-100uL |
| Product Name | Polycystin 2 Polyclonal Antibody, AbBy Fluor-750 Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Cow, Pig, Horse, Rabbit, Zebrafish |
| Specifications | |
| Conjugation | AbBy Fluor-750 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Polycystin 2 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 5311 |
| Swiss Prot | Q13563 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | polycystic kidney disease 2; TRPP2; APKD2, C030034P18RIK, MGC138466, MGC138468, PC2, PKD2 (includes EG:5311), PKD4, POLYCISTIN-2, POLYCYSTIN 2, RGD1559992, TRPP2; Polycystic kidney disease 2 protein homolog; PC2. |
| Background | Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Functions as a calcium permeable cation channel. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is Polycystin 2 Polyclonal Antibody, AbBy Fluor-750 Conjugated (bs-24450R-BF750) validated for, and at what dilution?
bs-24450R-BF750 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Polycystin 2 Polyclonal Antibody, AbBy Fluor-750 Conjugated (bs-24450R-BF750) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat, Cow, Pig, Horse, Rabbit, Zebrafish.
How should bs-24450R-BF750 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Polycystin 2 Polyclonal Antibody, AbBy Fluor-750 Conjugated (bs-24450R-BF750)?
KLH conjugated synthetic peptide derived from human Polycystin 2
What are the excitation and emission wavelengths of the AbBy Fluor-750 conjugate (bs-24450R-BF750)?
AbBy Fluor-750 on bs-24450R-BF750: excitation / emission 749nm/775nm.