CLEC7A Polyclonal Antibody, AbBy Fluor-405 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-2455R-BF405 |
| Product Name | CLEC7A Polyclonal Antibody, AbBy Fluor-405 Conjugated |
| Applications |
WB
FCM
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | AbBy Fluor-405 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Beta-glucan receptor |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 64581 |
| Swiss Prot | Q9BXN2 |
| Subcellular location | Cell membrane |
| Synonyms | BGR; CD369; CANDF4; DECTIN1; CLECSF12; C-type lectin domain family 7 member A; Beta-glucan receptor; C-type lectin superfamily member 12; Dendritic cell-associated C-type lectin 1; DC-associated C-type lectin 1; Dectin-1; CLEC7A; UNQ539/PRO1082 |
| Background | Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity). |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is CLEC7A Polyclonal Antibody, AbBy Fluor-405 Conjugated (bs-2455R-BF405) validated for, and at what dilution?
bs-2455R-BF405 is validated for WB (1:300-5000); FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does CLEC7A Polyclonal Antibody, AbBy Fluor-405 Conjugated (bs-2455R-BF405) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-2455R-BF405 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise CLEC7A Polyclonal Antibody, AbBy Fluor-405 Conjugated (bs-2455R-BF405)?
KLH conjugated synthetic peptide derived from human Beta-glucan receptor
What are the excitation and emission wavelengths of the AbBy Fluor-405 conjugate (bs-2455R-BF405)?
AbBy Fluor-405 on bs-2455R-BF405: excitation / emission 401nm/421nm.