PAWR Polyclonal Antibody, HRP Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-25044R-HRP |
| Product Name | PAWR Polyclonal Antibody, HRP Conjugated |
| Applications |
WB
ELISA
|
| Reactivity | Human, Mouse |
| Predicted Reactivity | Rat, Cow, Rabbit |
| Specifications | |
| Conjugation | HRP |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human PAWR |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | Q96IZ0 |
| Swiss Prot | 5074 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | 2310001G03Rik ; PAR 4 ; PAR-4 ; Pawr ; PAWR_HUMAN ; PRKC Apoptosis WT1 Regulator ; PRKC apoptosis WT1 regulator protein ; Prostate apoptosis response 4 protein ; Prostate apoptosis response protein 4 ; prostate apoptosis response protein PAR-4 ; Transcriptional repressor Par-4-like protein PAWR ; Transcriptional repressor PAR4 ; WT1 Interacting Protein |
| Background | Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down-regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1. |
| Application Dilution | |
| WB | 1:300-5000 |
| ELISA | 1:500-1000 |
Frequently asked questions
Which applications is PAWR Polyclonal Antibody, HRP Conjugated (bs-25044R-HRP) validated for, and at what dilution?
bs-25044R-HRP is validated for WB (1:300-5000); ELISA (1:500-1000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does PAWR Polyclonal Antibody, HRP Conjugated (bs-25044R-HRP) react with?
Tested reactivity: Human, Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Rat, Cow, Rabbit.
How should bs-25044R-HRP be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise PAWR Polyclonal Antibody, HRP Conjugated (bs-25044R-HRP)?
KLH conjugated synthetic peptide derived from human PAWR