ROS1 Polyclonal Antibody, PerCP Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-2504R-PerCP-100uL |
| Product Name | ROS1 Polyclonal Antibody, PerCP Conjugated |
| Applications |
WB
FCM
|
| Reactivity | Human, Rat |
| Specifications | |
| Conjugation | PerCP |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human c-Ros |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 6098 |
| Swiss Prot | P08922 |
| Subcellular location | Cell membrane |
| Synonyms | ROS; MCF3; c-ros-1; Proto-oncogene tyrosine-protein kinase ROS; Proto-oncogene c-Ros; Proto-oncogene c-Ros-1; Receptor tyrosine kinase c-ros oncogene 1; c-Ros receptor tyrosine kinase; ROS1 |
| Background | Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2. |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is ROS1 Polyclonal Antibody, PerCP Conjugated (bs-2504R-PerCP) validated for, and at what dilution?
bs-2504R-PerCP is validated for WB (1:300-5000); FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does ROS1 Polyclonal Antibody, PerCP Conjugated (bs-2504R-PerCP) react with?
Tested reactivity: Human, Rat.
How should bs-2504R-PerCP be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ROS1 Polyclonal Antibody, PerCP Conjugated (bs-2504R-PerCP)?
KLH conjugated synthetic peptide derived from human c-Ros
What are the excitation and emission wavelengths of the PerCP conjugate (bs-2504R-PerCP)?
PerCP on bs-2504R-PerCP: excitation / emission 482nm/677nm.