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Caspase 3 precursor Polyclonal Antibody

Applications

  • WB
  • ELISA

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-2593R
Product Name Caspase 3 precursor Polyclonal Antibody
Applications WB, ELISA
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from rat Caspase 3
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 25402
Swiss Prot P55213
Subcellular location Cytoplasm
Synonyms Lice; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; IRP; Protein Yama; SREBP cleavage activity 1; SCA-1; Casp3; Cpp32
Background Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity).
Application Dilution
WB 1:300-5000
ELISA 1:500-1000