Langerin Polyclonal Antibody, AbBy Fluor-488 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-2650R-BF488 |
| Product Name | Langerin Polyclonal Antibody, AbBy Fluor-488 Conjugated |
| Applications |
WB
|
| Reactivity | Mouse |
| Predicted Reactivity | Human, Rat |
| Specifications | |
| Conjugation | AbBy Fluor-488 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human CD207 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 50489 |
| Swiss Prot | Q9UJ71 |
| Subcellular location | Cell membrane |
| Synonyms | CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207 |
| Background | Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is Langerin Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-2650R-BF488) validated for, and at what dilution?
bs-2650R-BF488 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Langerin Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-2650R-BF488) react with?
Tested reactivity: Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Human, Rat.
How should bs-2650R-BF488 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Langerin Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-2650R-BF488)?
KLH conjugated synthetic peptide derived from human CD207
What are the excitation and emission wavelengths of the AbBy Fluor-488 conjugate (bs-2650R-BF488)?
AbBy Fluor-488 on bs-2650R-BF488: excitation / emission 499nm/519nm.