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Sema6A Polyclonal Antibody, HRP Conjugated

Applications

  • ELISA
  • IHC-P
  • IHC-F

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Dog
  • Cow
  • Pig
  • Rabbit
Overview
Catalog # bs-2701R-HRP
Product Name Sema6A Polyclonal Antibody, HRP Conjugated
Applications ELISA, IHC-P, IHC-F
Predicted Reactivity Human, Mouse, Rat, Dog, Cow, Pig, Rabbit
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Sema6A
Immunogen Range 301-400/1030
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 57556
Subcellular location Cell membrane
Synonyms semaphorin 6A; Sema Q; Sema VIA; SEMA6A-1; Semaphorin 6A-1; Semaphorin Q; Semaphorin VIA.
Background SEMA6A belongs to a subfamily characterized by an extracellular semaphorin domain, a transmembrane domain, and a long cytoplasmic tail. Members of this class can repel sympathetic and dorsal root ganglion axons in vitro, consistent with a traditional role as guidance signals. However, the length of the cytoplasmic tail, which includes an EVL-binding site in SEMA6A and an Src-binding site in SEMA6B, suggests that these semaphorins may also function as receptors. SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection. SEMA6A directly links the Ena/VASP and the semaphorin protein families since the SEMA6A protein is capable of selective binding to the protein EVL (Ena/VASP-like protein.
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500