CD108 Polyclonal Antibody, PE-Cy5 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-2702R-PE-Cy5-100uL |
| Product Name | CD108 Polyclonal Antibody, PE-Cy5 Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Dog, Cow |
| Specifications | |
| Conjugation | PE-Cy5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Semaphorin 7A |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 8482 |
| Swiss Prot | O75326 |
| Subcellular location | Cell membrane, Extracellular matrix |
| Synonyms | JMH; CD108; SEMAL; CDw108; SEMAK1; H-Sema-L; H-SEMA-K1; Semaphorin-7A; JMH blood group antigen; John-Milton-Hargen human blood group Ag; Semaphorin-K1; Sema K1; Semaphorin-L; Sema L; SEMA7A |
| Background | Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is CD108 Polyclonal Antibody, PE-Cy5 Conjugated (bs-2702R-PE-Cy5) validated for, and at what dilution?
bs-2702R-PE-Cy5 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does CD108 Polyclonal Antibody, PE-Cy5 Conjugated (bs-2702R-PE-Cy5) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat, Dog, Cow.
How should bs-2702R-PE-Cy5 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise CD108 Polyclonal Antibody, PE-Cy5 Conjugated (bs-2702R-PE-Cy5)?
KLH conjugated synthetic peptide derived from human Semaphorin 7A
What are the excitation and emission wavelengths of the PE-Cy5 conjugate (bs-2702R-PE-Cy5)?
PE-Cy5 on bs-2702R-PE-Cy5: excitation / emission 488nm/670nm.