CACNA1G Polyclonal Antibody, AbBy Fluor-405 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-2781R-BF405-100uL |
| Product Name | CACNA1G Polyclonal Antibody, AbBy Fluor-405 Conjugated |
| Applications |
FCM
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Specificity | Possible cross-reactivity with CACNA1H and CACNA1I |
| Reactivity | Human, Mouse, Rat |
| Predicted Reactivity | Dog, Cow |
| Specifications | |
| Conjugation | AbBy Fluor-405 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human CACNA1G/Cav31 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 8913 |
| Swiss Prot | O43497 |
| Subcellular location | Cell membrane |
| Synonyms | NBR13; Cav3.1; Ca(V)T.1; Voltage-dependent T-type calcium channel subunit alpha-1G; Cav3.1c; Voltage-gated calcium channel subunit alpha Cav3.1; CACNA1G; KIAA1123 |
| Background | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channel is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. |
| Application Dilution | |
| FCM | 1:20-100 |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is CACNA1G Polyclonal Antibody, AbBy Fluor-405 Conjugated (bs-2781R-BF405) validated for, and at what dilution?
bs-2781R-BF405 is validated for FCM (1:20-100); IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does CACNA1G Polyclonal Antibody, AbBy Fluor-405 Conjugated (bs-2781R-BF405) react with?
Tested reactivity: Human, Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Dog, Cow.
How should bs-2781R-BF405 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise CACNA1G Polyclonal Antibody, AbBy Fluor-405 Conjugated (bs-2781R-BF405)?
KLH conjugated synthetic peptide derived from human CACNA1G/Cav31
What are the excitation and emission wavelengths of the AbBy Fluor-405 conjugate (bs-2781R-BF405)?
AbBy Fluor-405 on bs-2781R-BF405: excitation / emission 401nm/421nm.