| Overview |
| bs-2810R-RBITC |
| HDAC5 Polyclonal Antibody, RBITC Conjugated |
| WB, IF |
| Human, Mouse, Rat, Bovine |
| Specifications |
| RBITC |
| Rabbit |
| KLH conjugated synthetic peptide derived from human HDAC5 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 9759, 10014 |
| P56524, Q9UQL6 |
| Cytoplasm, Nucleus |
| HDAC4: Histone deacetylase 4, HD4
HDAC 5; Histone deacetylase 5, HD5, Antigen NY-CO-9 |
| Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].. |
| Application Dilution |
| WB |
|
| IF |
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