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HDAC5 Polyclonal Antibody, AbBy Fluor-405 Conjugated

Applications

  • WB
  • IF

Reactivity

  • Human
  • Mouse
  • Rat
  • Bovine
Overview
Catalog # bs-2810R-BF405
Product Name HDAC5 Polyclonal Antibody, AbBy Fluor-405 Conjugated
Applications WB, IF
Reactivity Human, Mouse, Rat, Bovine
Specifications
Conjugation AbBy Fluor-405
Host Rabbit
Source KLH conjugated synthetic peptide derived from human HDAC5
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 9759, 10014
Swiss Prot P56524, Q9UQL6
Subcellular location Cytoplasm, Nucleus
Synonyms HDAC4: Histone deacetylase 4, HD4 HDAC 5; Histone deacetylase 5, HD5, Antigen NY-CO-9
Background Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]..
Application Dilution
WB
IF