ARHG7 Polyclonal Antibody, PerCP-Cy5.5 Conjugated
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-2936R-PerCP-Cy5.5-100uL |
| Product Name | ARHG7 Polyclonal Antibody, PerCP-Cy5.5 Conjugated |
| Applications |
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Predicted Reactivity | Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit |
| Specifications | |
| Conjugation | PerCP-Cy5.5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human ARHG7. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 8874 |
| Subcellular location | Cytoplasm |
| Synonyms | ARHG7_HUMAN; ARHG7; ARHGEF 7; ARHGEF7; Beta pix; betaPix; betaPix-b; betaPix-c; Cool; COOL1; P50 antibody P50BP; P85; P85COOL1; P85SPR; PAK interacting exchange factor beta; PAK3; Pak3bp; PAK3BP; PIX; PIXB; Rho guanine nucleotide exchange factor GEF 7; Rho guanine nucleotide exchange factor GEF 7b; Rho guanine nucleotide exchange factor GEF7; Rho guanine nucleotide exchange factor 7; SH3 domain containing proline rich protein; Nbla10314; KIAA0142. |
| Background | ARHGEF7 is a p21-activated protein kinase (Pak)-interacting exchange factor that has been identified as a putative guanine nucleotide exchange factor (GEF) for Rac/Cdc42. It is expressed ubiquitously in all the tissue examined and other isoforms are expressed mainly in the central nervous system. Regulated phosphorylation of ARHGEF7 is necessary to maintain the balance between normal signalling by EGFR and Src versus aberrant growth and transformation.Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene, but some of their full-length sequences have not been determined. |
| Application Dilution | |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is ARHG7 Polyclonal Antibody, PerCP-Cy5.5 Conjugated (BS-2936R-PERCP-CY5-5) validated for, and at what dilution?
BS-2936R-PERCP-CY5-5 is validated for IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
How should BS-2936R-PERCP-CY5-5 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ARHG7 Polyclonal Antibody, PerCP-Cy5.5 Conjugated (BS-2936R-PERCP-CY5-5)?
KLH conjugated synthetic peptide derived from human ARHG7.
What are the excitation and emission wavelengths of the PerCP-Cy5.5 conjugate (BS-2936R-PERCP-CY5-5)?
PerCP-Cy5.5 on BS-2936R-PERCP-CY5-5: excitation / emission 482nm/694nm.