14-3-3 zeta / delta (Ser58) Antibody


  • WB
  • FCM


  • Human

Predicted Reactivity

  • Mouse
  • Rat
  • Dog
  • Cow
  • Horse
  • Chicken
  • Rabbit
Catalog # bs-3000R
Product Name 14-3-3 zeta / delta (Ser58) Antibody
Applications WB, ELISA, FCM
Specificity This antibody will react with all 14-3-3 proteins containing the conserved motif RS(S-p)WR.
Reactivity Human
Predicted Reactivity Mouse, Rat, Dog, Cow, Horse, Chicken, Rabbit
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic phosphopeptide derived from human 14-3-3 protein zeta/delta around the phosphorylation site of Ser58 [RS(p-S)WR]
Modification Site Ser58
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID 7534, 7529, 10971
Subcellular location Cytoplasm
Synonyms YWHAEphospho S58; YWHAZphospho S58; 14 3 3; 14 3 3 protein beta; 14 3 3 protein beta/alpha; 14 3 3 protein zeta; 14-3-3 protein beta/alpha; KCIP 1; Protein 1054; Protein kinase C inhibitor protein 1; YWHAB; YWHAZ; GW128; HS1; KCIP-1; YWHAE; YWHAA; 1433Z_HUMAN; Full=14-3-3 protein zeta/delta; Protein kinase C inhibitor protein 1; KCIP-1.
Background Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100