Receive 30% off all Monoclonal IHC antibodies with code "MONO-IHC-30"! Offer valid for US customers and available internationally through distributors.

phospho-Bax (Ser184) Polyclonal Antibody, PE-Cy7 Conjugated

Applications

  • WB

Reactivity

  • Human
  • Mouse
  • Rat

Predicted Reactivity

  • Dog
  • Cow
  • Sheep
  • Pig
Overview
Catalog # bs-3010R-PE-Cy7
Product Name phospho-Bax (Ser184) Polyclonal Antibody, PE-Cy7 Conjugated
Applications WB
Reactivity Human, Mouse, Rat
Predicted Reactivity Dog, Cow, Sheep, Pig
Specifications
Conjugation PE-Cy7
Host Rabbit
Source KLH conjugated synthetic phosphopeptide derived from human Bax around the phosphorylation site of Ser184
Modification Site Ser184
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 581
Swiss Prot Q07812
Subcellular location Cytoplasm, Cell membrane
Synonyms BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BAX
Background Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Application Dilution
WB 1:300-5000