Overview |
bs-3010R |
Bax (Ser184) Polyclonal Antibody |
WB, ELISA, FCM |
Human, Mouse, Rat |
Dog, Cow, Sheep, Pig |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic phosphopeptide derived from human Bax around the phosphorylation site of Ser184 |
Ser184 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
Store at -20°C for 12 months.. |
Target |
581 |
Q07812 |
Cytoplasm, Cell membrane |
BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BAX |
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. |
Application Dilution |
WB |
1:300-1000 |
ELISA |
1:500-1000 |
FCM |
1:20-100 |