AMPK beta 1 (Ser108) Polyclonal Antibody, Cy5 Conjugated

Applications

IF(IHC-P)
IF(IHC-F)
IF(ICC)

Reactivity

Mouse
Rat

Overview
Catalog #	bs-3026R-Cy5
Product Name	AMPK beta 1 (Ser108) Polyclonal Antibody, Cy5 Conjugated
Applications	IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity	Mouse, Rat
Specifications
Conjugation	Cy5
Host	Rabbit
Source	KLH conjugated synthetic phosphopeptide derived from mouse AMPK beta 1 around the phosphorylation site of Ser108
Modification Site	Ser108
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID	19079
Subcellular location	Cytoplasm, Nucleus
Synonyms	PRKAB1phospho S108; PRKAB1S108; AMPK beta 1Ser108; p-AMPK beta 1Ser108; p-AMPK beta 1S108; 5 AMP activated protein kinase subunit beta 1; AMPK; AMPK beta 1 chain; AMPKb; HAMPKb; PRKAB1; 5'-AMP-activated protein kinase subunit beta-1; AMP-activated protein kinase beta subunit; protein kinase, AMP-activated, noncatalytic, beta-1; AMPK beta -1 chain; 5'-AMP-activated protein kinase beta-1 subunit; AMPKb; AMPK subunit beta-1; AAKB1_RAT.
Background	The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008].
Application Dilution
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200

Search our catalog of hundreds of thousands of products