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GSK-3 Beta(Thr390) Polyclonal Antibody, PE Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Human
  • Rat

Predicted Reactivity

  • Dog
  • Pig
  • Chicken
  • Rabbit
  • Guinea Pig
Overview
Catalog # bs-3148R-PE
Product Name GSK-3 Beta(Thr390) Polyclonal Antibody, PE Conjugated
Applications WB, FCM
Reactivity Human, Rat
Predicted Reactivity Dog, Pig, Chicken, Rabbit, Guinea Pig
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated Synthesised phosphopeptide derived from human GSK-3 Beta around the phosphorylation site of Thr390
Modification Site Thr390
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 2932
Subcellular location Cytoplasm, Nucleus, Cell membrane
Synonyms GSK3B(Thr390); GSK3B(T390); p-GSK-3 Beta(Thr390); p-GSK-3 beta(T390); Glycogen synthase kinase 3 beta; GSK 3 beta; GSK 3B; GSK3B; GSK3B protein; GSK3beta isoform; GSK3 beta; Glycogen synthase kinase-3 beta; GSK-3 beta; GSK3B_HUMAN.
Background Glycogen synthase kinase 3 (GSK3) is a proline directed serine threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. GSK3 has been implicated in fundamental cell processes such as cell fate determination, metabolism, transcriptional control and oncogenesis. Two isoforms, alpha (GSK3A; OMIM 606784) and beta, show a high degree of amino acid homology within their catalytic domains. GSK3B is involved in energy metabolism, neuronal cell development and body pattern formation.
Application Dilution
WB 1:300-5000
FCM 1:20-100