Phospho-PSD95 (Tyr236 + Tyr240) Polyclonal Antibody, AbBy Fluor-405 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-3349R-BF405-100uL |
| Product Name | Phospho-PSD95 (Tyr236 + Tyr240) Polyclonal Antibody, AbBy Fluor-405 Conjugated |
| Applications |
FCM
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Reactivity | Human, Mouse, Rat |
| Predicted Reactivity | Dog, Cow, Pig, Rabbit |
| Specifications | |
| Conjugation | AbBy Fluor-405 |
| Host | Rabbit |
| Source | KLH conjugated synthetic phosphopeptide derived from human PSD95 around the phosphorylation site of Tyr236/Tyr240 |
| Modification Site | Tyr236 + Tyr240 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 1742 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | Discs large homolog 4; DLG 4; DLG4; Human post-synaptic density protein 95 ; Postsynaptic density protein 95; PSD 95; PSD-95; SAP 90; SAP90; Synapse associated protein 90. |
| Background | postsynaptic density protein 95 is a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway. This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with DLG2. With DLG2 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. |
| Application Dilution | |
| FCM | 1:20-100 |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is Phospho-PSD95 (Tyr236 + Tyr240) Polyclonal Antibody, AbBy Fluor-405 Conjugated (bs-3349R-BF405) validated for, and at what dilution?
bs-3349R-BF405 is validated for FCM (1:20-100); IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Phospho-PSD95 (Tyr236 + Tyr240) Polyclonal Antibody, AbBy Fluor-405 Conjugated (bs-3349R-BF405) react with?
Tested reactivity: Human, Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Dog, Cow, Pig, Rabbit.
How should bs-3349R-BF405 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Phospho-PSD95 (Tyr236 + Tyr240) Polyclonal Antibody, AbBy Fluor-405 Conjugated (bs-3349R-BF405)?
KLH conjugated synthetic phosphopeptide derived from human PSD95 around the phosphorylation site of Tyr236/Tyr240
What are the excitation and emission wavelengths of the AbBy Fluor-405 conjugate (bs-3349R-BF405)?
AbBy Fluor-405 on bs-3349R-BF405: excitation / emission 401nm/421nm.