| Overview |
| bs-3405R-Cy7 |
| Phospho-PTPN11 (Tyr580) Polyclonal Antibody, Cy7 Conjugated |
| WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
| This phosphorylation site is homologous across the listed cross reactive species. |
| Human, Mouse, Rat |
| Horse, Chicken |
| Specifications |
| Cy7 |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human PTPN11 around the phosphorylation site of Tyr584 |
| Tyr584 |
| Polyclonal |
| #REF! |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 5781 |
| Q06124 |
| Cytoplasm |
| CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; PTP-2C; SHP-2; PTPN11; SHPTP2 |
| Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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