| Overview |
| bs-3466R |
| VASP(Ser239) Polyclonal Antibody |
| WB, ELISA |
| This phosphorylation site is homologous to that of Ser235 in Mouse and Ser236 in Rat. |
| Mouse |
| Human, Rat, Dog, Cow |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human VASP around the phosphorylation site of Ser239 |
| Ser239 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 7408 |
| P50552 |
| Cytoplasm |
| Vasodilator-stimulated phosphoprotein; VASP |
| Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation. |
| Application Dilution |
| WB |
1:300-5000 |
| ELISA |
1:500-1000 |
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