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PLCG1 Polyclonal Antibody, APC Conjugated

Applications

  • WB
  • IF(IHC-P)

Reactivity

  • Mouse

Predicted Reactivity

  • Human
  • Rat
  • Cow
  • Pig
  • GuineaPig
Overview
Catalog # bs-3533R-APC
Product Name PLCG1 Polyclonal Antibody, APC Conjugated
Applications
WB IF(IHC-P)
Reactivity Mouse
Predicted Reactivity Human, Rat, Cow, Pig, GuineaPig
Specifications
Conjugation APC
Host Rabbit
Source KLH conjugated synthetic peptide derived from human PLC gamma 1
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 5335
Synonyms PLC gamma 1; 1 phosphatidyl D myo inositol 4 5 bisphosphate; 1 phosphatidylinositol 4 5 bisphosphate; 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; NCKAP3; phosphatidylinositol phospholipase C; phosphodiesterase gamma 1; phosphoinositidase C; phosphoinositide phospholipase C; Phosphoinositide phospholipase C-gamma-1; Phospholipase C 148; Phospholipase C 148; phospholipase C gamma 1 formerly subtype 148; Phospholipase C gamma 1; Phospholipase C gamma 1; phospholipase C-148; Phospholipase C-gamma-1; Phospholipase C-II; PLC 1; PLC 148; PLC 148; PLC gamma 1; PLC II; PLC II; PLC-148; PLC-gamma-1; PLC-II; PLC1; PLC148; PLCG 1; PLCG 1; PLCG1; PLCG1_HUMAN; PLCgamma1; PLCII; triphosphoinositide phosphodiesterase.
Background The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Application Dilution
WB
IF(IHC-P)

Frequently asked questions

Which applications is PLCG1 Polyclonal Antibody, APC Conjugated (bs-3533R-APC) validated for, and at what dilution?

bs-3533R-APC is validated for WB, IF(IHC-P).

Which species does PLCG1 Polyclonal Antibody, APC Conjugated (bs-3533R-APC) react with?

Tested reactivity: Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Human, Rat, Cow, Pig, GuineaPig.

How should bs-3533R-APC be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise PLCG1 Polyclonal Antibody, APC Conjugated (bs-3533R-APC)?

KLH conjugated synthetic peptide derived from human PLC gamma 1