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VASP Polyclonal Antibody, PE Conjugated

Applications

  • WB

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Dog
  • Cow
Overview
Catalog # bs-3603R-PE
Product Name VASP Polyclonal Antibody, PE Conjugated
Applications WB
Predicted Reactivity Human, Mouse, Rat, Dog, Cow
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human VASP
Immunogen Range 251-350/380
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 7408
Subcellular location Cytoplasm, Cell membrane
Synonyms Vasodilator stimulated phosphoprotein_ Vasodilator-stimulated phosphoprotein_ VASP_ VASP_HUMAN.
Background Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq].
Application Dilution
WB 1:300-5000