F11R/JAM-A/CD321 Polyclonal Antibody, APC Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-3651R-APC-100uL |
| Product Name | F11R/JAM-A/CD321 Polyclonal Antibody, APC Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Dog, Cow, Pig |
| Specifications | |
| Conjugation | APC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Junctional Adhesion Molecule 1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 50848 |
| Swiss Prot | Q9Y624 |
| Subcellular location | Cell membrane |
| Synonyms | JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; F11R; UNQ264/PRO301 |
| Background | Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is F11R/JAM-A/CD321 Polyclonal Antibody, APC Conjugated (bs-3651R-APC) validated for, and at what dilution?
bs-3651R-APC is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does F11R/JAM-A/CD321 Polyclonal Antibody, APC Conjugated (bs-3651R-APC) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat, Dog, Cow, Pig.
How should bs-3651R-APC be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise F11R/JAM-A/CD321 Polyclonal Antibody, APC Conjugated (bs-3651R-APC)?
KLH conjugated synthetic peptide derived from human Junctional Adhesion Molecule 1
What are the excitation and emission wavelengths of the APC conjugate (bs-3651R-APC)?
APC on bs-3651R-APC: excitation / emission 650nm/660nm.