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thymidine phosphorylase Polyclonal Antibody, PE-Cy5 Conjugated

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bs-3809R-PE-Cy5
Product Name thymidine phosphorylase Polyclonal Antibody, PE-Cy5 Conjugated
Applications
WB
Reactivity Human
Specifications
Conjugation PE-Cy5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Thymidine Phosphorylase
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 1890
Subcellular location Cytoplasm
Synonyms ECGF 1; PDEGF; ECGF1; Endothelial cell growth factor 1; Endothelial cell growth factor 1 platelet derived; Gliostatin; hPD ECGF; MNGIE; PD ECGF; PDECGF; PDEGF; Platelet derived endothelial growth factor; TdRPase; TP; TYMP; Thymidine Phosphorylase; TYPH_HUMAN; TdRPase.
Background In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
Application Dilution
WB 1:300-5000

Frequently asked questions

Which applications is thymidine phosphorylase Polyclonal Antibody, PE-Cy5 Conjugated (bs-3809R-PE-Cy5) validated for, and at what dilution?

bs-3809R-PE-Cy5 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does thymidine phosphorylase Polyclonal Antibody, PE-Cy5 Conjugated (bs-3809R-PE-Cy5) react with?

Tested reactivity: Human.

How should bs-3809R-PE-Cy5 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise thymidine phosphorylase Polyclonal Antibody, PE-Cy5 Conjugated (bs-3809R-PE-Cy5)?

KLH conjugated synthetic peptide derived from human Thymidine Phosphorylase

What are the excitation and emission wavelengths of the PE-Cy5 conjugate (bs-3809R-PE-Cy5)?

PE-Cy5 on bs-3809R-PE-Cy5: excitation / emission 488nm/670nm.