Sorbitol Dehydrogenase Polyclonal Antibody, PE-Cy5 Conjugated
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-3829R-PE-Cy5-100uL |
| Product Name | Sorbitol Dehydrogenase Polyclonal Antibody, PE-Cy5 Conjugated |
| Applications |
WB
|
| Predicted Reactivity | Human, Mouse, Rat, Dog, Cow, Pig, Horse |
| Specifications | |
| Conjugation | PE-Cy5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Sorbitol Dehydrogenase |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 6390 |
| Subcellular location | Cytoplasm, Secreted, Cell membrane |
| Synonyms | L iditol 2 dehydrogenase; SDH; SORD 1; SORD; SORD1. DHSO_HUMAN |
| Background | Sorbitol dehydrogenase (SDH), a member of the medium-chain dehydrogenase/reductase protein family and the second enzyme of the polyol pathway of glucose metabolism, converts sorbitol to fructose strictly using NAD(+) as coenzyme. SDH is expressed almost ubiquitously in all mammalian tissues. The enzyme has attracted considerable interest due to its implication in the development of diabetic complications as the polyol pathway is particularly active in hyperglycemic states. Although SORD is closely related to the class I long-chain alcohol dehydrogenases, it differs in substrate specificity, catalyzing polyols such as sorbitol and xylitol but having no activity towards primary alcohols. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is Sorbitol Dehydrogenase Polyclonal Antibody, PE-Cy5 Conjugated (bs-3829R-PE-Cy5) validated for, and at what dilution?
bs-3829R-PE-Cy5 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
How should bs-3829R-PE-Cy5 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Sorbitol Dehydrogenase Polyclonal Antibody, PE-Cy5 Conjugated (bs-3829R-PE-Cy5)?
KLH conjugated synthetic peptide derived from human Sorbitol Dehydrogenase
What are the excitation and emission wavelengths of the PE-Cy5 conjugate (bs-3829R-PE-Cy5)?
PE-Cy5 on bs-3829R-PE-Cy5: excitation / emission 488nm/670nm.