G6PC Polyclonal Antibody, APC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-4044R-APC |
| Product Name | G6PC Polyclonal Antibody, APC Conjugated |
| Applications |
WB
IF
|
| Reactivity | Human, Mouse, Rat, Bovine, Dog, Pig |
| Specifications | |
| Conjugation | APC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase alpha |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 2538 |
| Subcellular location | Lumenal |
| Synonyms | glucose-6-phosphatase, catalytic subunit; GSD1; AW107337; G-6-Pase; G6Pase; G6Pase-alpha; g6pc; G6PC_HUMAN; G6PT; Glucose-6-phosphatase alpha; Glucose-6-phosphatase; GSD1a; MGC163350; MGC93613; RP23-281C18.19. |
| Background | Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-, a second form, designated G6Pase-_, contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-_, also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-_ hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-_ may play an integral role in diabetes and glycogen storage diseases (GSDs). |
| Application Dilution | |
| WB | |
| IF | |
Frequently asked questions
Which applications is G6PC Polyclonal Antibody, APC Conjugated (bs-4044R-APC) validated for, and at what dilution?
bs-4044R-APC is validated for WB, IF.
Which species does G6PC Polyclonal Antibody, APC Conjugated (bs-4044R-APC) react with?
Tested reactivity: Human, Mouse, Rat, Bovine, Dog, Pig.
How should bs-4044R-APC be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise G6PC Polyclonal Antibody, APC Conjugated (bs-4044R-APC)?
KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase alpha