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S100B, PE-Cy5 Conjugated

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bs-41191R-PE-Cy5
Product Name S100B, PE-Cy5 Conjugated
Applications WB
Reactivity Human
Specifications
Conjugation PE-Cy5
Host Rabbit
Source Recombinant human S100B protein
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1mg/ml
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 6285
Swiss Prot P04271
Subcellular location Cytoplasm, Nucleus
Synonyms NEF; Protein S100 B; Protein S100-B; S 100 calcium binding protein beta chain; S 100 protein beta chain; S 100 protein beta subunit; S-100 protein beta chain; S-100 protein subunit beta; S100; S100 calcium binding protein B; S100 calcium binding protein beta (neural); S100 calcium binding protein beta chain; S100 calcium-binding protein B; S100 protein beta chain; S100B_HUMAN; S100beta; S100 _; S100-_; S100_.
Background Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
Application Dilution
WB