Recombinant human Podocin, N-His, Biotin Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-41306P-Biotin-100ug |
| Product Name | Recombinant human Podocin, N-His, Biotin Conjugated |
| Applications |
OTHERS
|
| Reactivity | Others |
| Specifications | |
| Conjugation | Biotin |
| Source | Recombinant human Podocin protein is expressed in E.coli with N-His. It contains the amino acid sequence of 125-383/383 |
| Storage Buffer | Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization. |
| Target | |
| Swiss Prot | Q9NP85 |
| Background | Podocin is an important member of a group of proteins shown to be associated with the slit diaphragm. Podocin belongs to the band 7 stomatin family of lipid raft-associated proteins. It is a hairpin like integral membrane protein with intracellular N and C termini. Podocin is located at the insertion site of the slit membrane, and is thought to act as a scaffold protein required to maintain or regulate the structural integrity of the slit diaphragm. It plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton. |