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Recombinant human Podocin, N-His, Biotin Conjugated

Applications

  • Others

Reactivity

  • Others
Overview
Catalog # bs-41306P-Biotin-100ug
Product Name Recombinant human Podocin, N-His, Biotin Conjugated
Applications Others
Reactivity Others
Specifications
Conjugation Biotin
Source Recombinant human Podocin protein is expressed in E.coli with N-His. It contains the amino acid sequence of 125-383/383
Storage Buffer Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.
Target
Swiss Prot Q9NP85
Background Podocin is an important member of a group of proteins shown to be associated with the slit diaphragm. Podocin belongs to the band 7 stomatin family of lipid raft-associated proteins. It is a hairpin like integral membrane protein with intracellular N and C termini. Podocin is located at the insertion site of the slit membrane, and is thought to act as a scaffold protein required to maintain or regulate the structural integrity of the slit diaphragm. It plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.