ZO-1 Polyclonal Antibody, PerCP Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-41327R-PerCP |
| Product Name | ZO-1 Polyclonal Antibody, PerCP Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | PerCP |
| Host | Rabbit |
| Source | Recombinant human ZO-1 protein |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 7082 |
| Swiss Prot | Q07157 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | ZO1_HUMAN; Tight junction protein ZO-1; TJP1; Tight junction protein 1; Zona occludens protein 1; Zonula occludens protein 1; ZO1 tight junction protein; |
| Background | This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017] |
| Application Dilution | |
| WB | |
Frequently asked questions
Which applications is ZO-1 Polyclonal Antibody, PerCP Conjugated (bs-41327R-PerCP) validated for, and at what dilution?
bs-41327R-PerCP is validated for WB.
Which species does ZO-1 Polyclonal Antibody, PerCP Conjugated (bs-41327R-PerCP) react with?
Tested reactivity: Human.
How should bs-41327R-PerCP be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ZO-1 Polyclonal Antibody, PerCP Conjugated (bs-41327R-PerCP)?
Recombinant human ZO-1 protein