Recombinan human ACE2 Protein

Applications

  • WB
  • ELISA

Reactivity

  • Human
Overview
Catalog # bs-41410P
Product Name Recombinan human ACE2 Protein
Applications WB, ELISA
Reactivity Human
Specifications
Conjugation Unconjugated
Source An E.coli expression system produces recombinant Human ACE2 Protein, and the target gene encoding amino acids 243-369 is expressed with His Tag.
Storage Buffer Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.
Storage Condition The product should be stored at -70°C or -20°C.
Target
Gene ID NP_001358344.1
Background Angiotensin-converting enzyme 2 (ACE2) is an enzyme attached to the outer surface (cell membranes) of cells in the lungs, arteries, heart, kidney, and intestines. ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II (a vasoconstrictor peptide) into angiotensin (1–7) (a vasodilator). ACE2 counters the activity of the related angiotensin-converting enzyme (ACE) by reducing the amount of angiotensin-II and increasing Ang(1-7) making it a promising drug target for treating cardiovascular diseases. ACE2 also serves as the entry point into cells for some coronaviruses including Severe acute respiratory syndrome coronavirus 2.